Khachanov won the pair's previous encounter in Paris - at 2018 Paris Masters, when the Russian claimed a straight-set win in the final to clinch the biggest title of his career until now.
Loew had criticized the additional friendlies this year, as they are downsizing his time window for training sessions. Additional training is of more value for a team in a transition process than test-matches Loew stated.
Nadal will face Sebastian Korda, the son of 1998 Australian Open winner Petr Korda, in the next round. The American youngster secured his first appearance in a Grand Slam round of 16 by beating fellow qualifier Pedro Martinez 6-4, 6-3, 6-1 to advance.
The visitor from Spisska Nova Ves was leading by 13 points at half-time which ultimately proved decisive, but the home team managed to fight the deficit and almost brought the game to a thrilling end despite having only five available players in the second half due to injuries and fouls. Enditem
Sunday's win and the midweek victory against Valladolid were largely thanks to goalkeeper Thibaut Courtois, who produced man of the match performances in both games to keep Madrid's rivals at bay.
Atletico Madrid at home to Villarreal is Saturday's most attractive game, with Luis Suarez likely to start in the Wanda Metropolitano as Atletico looks to improve on its flat showing away to Huesca in midweek.
With 3:04 left on the clock of the third period, Fujian kept chasing the score-line and trailed by 57-66, but Zhejiang reclaimed a double-digit advantage through Dong Ke'er's three-pointer.
In women's action, Petra Kvitova managed to return to the quarterfinals at Roland Garros for the first time since 2012 after a comfortable 6-2, 6-4 dismissal of China's Zhang Shuai in the opening match on Court Philippe-Chatrier on Monday.
Five Dongguan players scored in the double-digits. Dilana Dilishati had 19 points and eight boards. Shen Yi scored 18 points and dished out eight assists.
The club presented new signing Sergino Dest on Friday and the 19-year-old right back, who arrives from Ajax, is an option of starting on the bench on Sunday.
Cadiz and Granada shared the points in an Andalusian derby which began with German Sanchez's header for the visitors in the 27th minute before Ivan Alejo's driven shot assured Cadiz its first home point of the season three minutes after halftime.